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Jack Volker Greiner
Schepens Eye Research Institute, USA

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Prof. Dr. Dr. h.c. Hamid Mattiello
Swiss School of Business and Management (SSBM) Geneva, Switzerland

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Jimei University

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University of Naples, Italy

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University of South China, China

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Icahn School of Medicine at Mount Sinai, USA

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School of Civil Engineering and Architecture, Wuyi University, China

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University of Petrosani, Romania

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Northwestern Polytechnical University, China

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Al-Baha University, Saudi Arabia

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Nanjing Medical University, China

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Yamagata University, Japan

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Heriot-Watt University, UK

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The University of Tennessee Health Science Center, USA

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The University of China Agricultural, Beijing

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Indexed In

A Novel Theranostic Hypothesis In Ga-68 HCl For SARS-CoV-2

Research Article

Authors: Mohammed Al Rowaily*

Published: March 20, 2026

Abstract: Purpose: This Study Proposes A Novel Theranostic Approach Using Gallium-68 Chloride (⁶⁸GaCl₃) In Hydrochloric Acid (HCl) As A Potential Treatment For SARS-CoV-2, Aiming To Explore Viral Inactivation Through Targeted Delivery In Acidic Environments. Procedures: Drawing From Existing Literature On SARS-CoV-2 Susceptibility To Acidic Environments And The Chemical Properties Of Gallium-68, A Hypothesis Was Formulated. A Research Proposal Was Created To Administer 5 ML Of ⁶⁸Ga/0.1 M HCl To COVID-19 Patients For Five Days, Using PET Imaging For Verification Of Targeting. Results: A Pilot Investigation Was Conducted Whereby Two Patients With Moderate Pneumonia Received A Single Intravenous Dose Of 5 ML Of ⁶⁸Ga-DOTATATE In A 0.1 M HCl Medium. PET/CT Imaging Showed Notable Accumulation Of The ⁶⁸Ga/HCl Complex In The Lungs, Specifically In Areas Of Inflammation, Confirming Successful Delivery To Viral Replication Sites. Conclusions: The Pilot Study Supports The Viability Of The Theranostic Approach In Targeting SARS-CoV-2. This Narrative Emphasizes The Importance Of Innovative Thinking During Health Crises And Highlights The Potential Of Repurposing Diagnostic Radionuclides For Therapeutic Applications Against Emerging Viral Threats.