Case of terminal breast cancer with systemic metastasis cured by vegetable and fruit juice

The patient is a woman in her 40s. She was diagnosed with left breast cancer in her 30s (1998) and underwent a left mastectomy. She began to cough around December 2010, and as a result of an examination, systemic metastasis was confirmed. The main cause was multiple metastases in the chest cavity, and bone metastases were also observed. In January 2011, treatment with Taxotere (80mg) was started at a hospital in Shikoku, with administration once every three weeks. However, the side effects were strong, so in June 2011, the dosage was reduced by 80% and changed to once every four weeks. In addition, the patient was taking 20-30mg of the painkiller narcotic MS Contin twice a day.

The patient first visited our hospital in June 2011. We recommended a diet therapy aimed at alkalinisation, and advised the patient to consume 10g of plum extract and 2 litres of homemade vegetable and fruit juice per day. We instructed the patient to always consume these in place of water or tea. During the course of treatment, the dosage of the anti-cancer drug was gradually reduced, and in June 2012 it was completely discontinued. No shrinkage of the tumour was observed for the first year after the start of treatment, but thereafter a rapid shrinkage of the tumour was confirmed. As of 2024, he has maintained his health for over 10 years without undergoing treatment.

In the case of advanced breast cancer, the prognosis often worsens when cytotoxic anticancer drugs are used for a long period of time. In this patient, the side effects were reduced and the patient’s immunity was restored by reducing the amount of anticancer drugs used, stopping them early, and switching to alkalinization therapy. This may have improved the patient’s prognosis. It is thought that the patient’s own immunity was restored by reducing the amount of anticancer drugs and alkalinizing the cancer microenvironment. The tumour microenvironment (TME) is generally highly acidic, and this environment promotes cancer growth. When alkaline food is consumed, there is a high possibility that the acidity of the TME will become alkaline. In order to alkalize the TME, the patients were instructed to eat a lot of vegetables and fruit with high Pral values. This is thought to have created an internal environment that was not favorable for cancer cells, and suppressed cancer growth [2, 3]. Furthermore, to boost the patients ‘immunity, they received intravenous infusions of vitamin C 2 to 4 times a month. This is thought to have suppressed the growth of cancer cells and promoted the patients’ natural healing power [4, 5].

Table 1: Wada Clinic: Five-year survival rate for 131 cases of stage 4 breast cancer, based on urine pH. Overall, it was 46.5%, with 63% for the pH 7 or higher group, 37.8% for the pH 6 to 7 group, and 0% for the pH 5 or lower group.

In the bodies of cancer patients, the interior of cancer cells is alkaline, while the surrounding area is acidic. It has been suggested that neutralizing this acidic environment may inhibit the activity of cancer cells. In the alkaline diet guidance for patients, the pH of the urine was measured to evaluate the progress of alkalisation. This is thought to have created an environment in which cancer cells are unlikely to survive, and contributed to the reduction of tumours.

Warburg, O. stated that cancer develops in areas where there is a lack of oxygen, but where there is a continuous supply of nutrients [1]. Based on this concept, if the microenvironment around the cancer becomes acidic, cancer treatment becomes extremely difficult [5, 6]. In the case reported here, the patient was able to achieve a complete recovery by alkalizing the acidic TME [7, 8]. Treatment for metastatic breast cancer generally involves the use of anti-cancer drugs. In this case, docetaxel was used, but the patient experienced very strong side effects. The 5-year survival rate for stage 4 is 38.7%. This is a significant decrease in survival rate compared to the 5-year survival rate for stage 3, which is 80.7%. It is said that cancer that has spread to other organs is difficult to completely cure, but this patient was cured completely through alkalinization therapy. The ‘alkalinization therapy’ that we advocate is effective both on its own and when added to conventional standard therapy. In the case of this report, it can be said that advanced recurrent breast cancer was completely cured through ‘alkalinization therapy’ alone [9, 10].

It is thought that the development of cancer is linked to intermittent oxygen deprivation, which causes cells to turn to glycolytic metabolism and leads to carcinogenesis. This process leads to the acidification of the tumour microenvironment (TME), which promotes cancer malignancy and drug resistance. We have reported that alkalinization therapy, which aims to neutralize this acidity, is effective.

1. Warburg O (1956) On the origin of cancer cells Science, 123(3191): 309-314.
2. Benjamin H. Parmenter, Michael Dymock, Tanushree Banerjee (2020) Performance of Predictive Equations and Biochemical Measures Quantifying Net Endogenous Acid Production and the Potential Renal Acid Load, Kidney International Reports 5: 1738–17
3. IA Osuna-Padillaa G Leal-Escobarb CA, Garza-Garcíac (2019) Dietary acid load: Mechanisms and evidence of its health repercussions, Nefrologia. 3 9(4): 343–354
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5. Hamaguchi R, Narui R, Wada H (2019) Effects of an Alkalization Therapy on Nivolumab in Esophago­gastric Junction Adenocarcinoma: A Case Report, Clinics of Oncology 2(1): 1-4.
6. Hamaguchi R, Narui R, Morikawa H. Wada H (2021) Improved Chemotherapy Outcomes of Patients With Small-cell Lung Cancer Treated with Combined Alkalization Therapy and Intravenous Vitamin C, Cancer Diag. Prog 1: 157-163
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8. Hiromi Wada, Toshihiro Okamoto and Reo Hamaguchi (2024) The wrong Diet Can Cause Cancer. However, we can cure cancer by changing our diet. The human body is a “dissipative structure, 2024, Global Journal of Nutrition & Food Science, ISSN: 2644-2981 DOI: 10.33552/GJNFS.2024.04.000597 , GJNFS.MS.ID.000597.
9. Hiromi Wada, Reo Hamaguchi, Shinji Umemoto (2023) The impact of alkalizing the acidic tumor microenvironment to improve efficacy of cancer treatment, Edited by, Published in Frontiers in Oncology, e-Book,
10. Wada H, Okamoto T, Isowa1 M, Narui R, Hiromasa Morikawa H, et al. (2024) Case of Stage 4 Lung Cancer with So-Called Spontaneous Regression -Usefulness of Alkalinization Therapy (2024) Global Journal of Nutrition & Food Science, ISSN: 2644-2981 DOI: 10.33552/GJNFS.202