Open Access Research Protocol

Study the Effect of Depakote Using Electrooculogram

Maryam Naser*, Sohar Koheilian and Aron Mahfelin

Department of Ophthalmology, Tehran Azad Medical Sciences, Iran

Corresponding Author

Received Date: May 09, 2019;  Published Date: May 16, 2019


Introduction: Depakote is an anticonvulsant drug usually used to treat seizure, bipolar disorders, migraine and epilepsy. Patients usually need to take this drug for a long time to control seizures in epilepsy and prevent severe headaches in migraine. There are some common side effects of Depakote such as Diarrhea, Double Vision, Dizziness, Tremor and change in menstrual periods. The aim of this study is to check retinal function in patients that are taking Depakote for a while.

Method: In this cross-sectional stud, 34 patients with a history of seizures and using Depakote for at least 6 months were included as a case group. 34 normal people were added to the research as a control group. We recorded electrooculography for all subject in the study and compared the result with two groups.

Results: The Arden Index (AI) in case group was 3.78± 0.82 and 3.18 ± 0.66 in control population that showed no statistically significant difference between two groups.

Conclusion: Based on the result of present study, one can conclude that using Depakote may have no adverse effect on retinal function.

Keywords:Electrooculography; Depakote; Seizure

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