A Case Report of Severe Intrahepatic Cholestasis of Pregnancy with Severe Liver Damage as the Main Manifestation
Received Date:June 25, 2021; Published Date: July 13, 2021
Background: Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder during pregnancy. Most ICP cases have good prognosis after delivery. The mother’s ICP symptoms and biochemical abnormalities usually resolve after delivery.
Case: This was a severe ICP with severe liver damage as the main manifestation. One week after childbirth, her liver damage did not gradually recover but gradually worsened. This case showed quite difference from the common ICP cases. We have not found similar case reports.
Conclusion: The particularity of the onset and outcome of this case, compared with the conventional ICP case, which gives us a new perspective on ICP.
Keywords: ICP; Pregnancy; Prognosis; Bile acids; Liver transaminases aspartate aminotransferase; Liver alanine aminotransferase
Abbreviations: ICP: Intrahepatic Cholestasis of Pregnancy; AST: transaminases aspartate aminotransferase; ALT: Alanine Aminotransferase; GDM: Gestational Diabetes Mellitus; LDH: Lactate Dehydrogenase; IgG: Immunoglobulin G; D1L1: Drug-induced Liver Injury; AIH: Autoimmune Hepatitis; AFLP: Acute Fatty Liver of Pregnancy