Open Access Case Report

A Rare Association of Marfan Syndrome with Papillary Carcinoma of Thyroid

Lendoye W*, Moujrid S, Radhi H, Abada R and Mahtar M

ENT Head and Neck Surgery department, Ibn Rochd University Hospital, Morocco

Corresponding Author

Received Date:March 07, 2022;  Published Date: June 07, 2022

Abstract

Marfan syndrome is a common genetic disorder involving a defciency of the structural extracellular matrix component fbrillin-1 and overactivation of the transforming growth factor-β signalling pathway. The growth factor-β signalling pathway also actively participates in malignant transformation. The aim of this work is to present a rare association observed in a 18-years-old patient treated in the ENT tertiary referral center of Casablanca, Morocco for a voluminous goiter and Marfan syndrome.

Keywords: papillary carcinoma; Marfan syndrome; Thyroid; Growth factor-β

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