Open Access Mini Review

Ear, Nose and Throat Approach in Autoimmune Blistering Diseases

Ismail Cem Temel1, Asli Bilgic-Temel2* and Dedee Frances Murrell2,3

1Sydney ENT Clinic, Sydney, Australia

2Department of Dermatology, St George Hospital, UNSW, Australia

3Faculty of Medicine, University of New South Wales, Australia

Corresponding Author

Received Date: October 08, 2018;  Published Date: September 10, 2018


Autoimmune blistering diseases (AIBD) are a group of rare blistering disorders of the skin and mucous membranes due to autoantibodies directed against specific proteins. Involvement of mucosal areas in AIBD significantly increases patient morbidity and mortality. Ear, nose and throat (ENT) examination should be a routine procedure to evaluate mucosal involvement in every AIBD. Patients should be asked whether they had oropharyngeal, ear, nose and throat symptoms and all patients should be evaluated for ENT manifestations by direct and endoscopic examination even in patients without symptoms.

Keywords: Autoimmune blistering diseases; Ear; Nose; Throat; Mucosal involvement

Abbreviations: AIBD: Autoimmune Blistering Diseases; IEBD: Intraepidermal Blistering Diseases; SEBD: Subepidermal Blistering Diseases; PV: Pemphigus Vulgaris; PF: Pemphigus Foliaceus; PNP: Paraneoplastic Pemphigus; BP: Bullous Pemphigoid; MMP: Mucous Membrane Pemphigoid; ENT: Ear, Nose and Throat; PDAI:Pemphigus Disease Area Index; ABSIS: Autoimmune Bullous Skin Disorder Intensity Score; DIF: Direct Immunofluorescence Microscopy; ELISA: Enzyme-linked Immunosorbent Assay

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