Osseous Heart- A Rare Case of Metastatic Osteosarcoma to the Heart

Osteosarcomas are uncommon malignant tumors of the bone that arise from the production of osteoid or immature bone by the malignant cells. In rare occasions this tumor metastasizes to other organs including the brain and lungs. Although hematogenous spread of osteosarcoma is well known, cardiovascular metastasis is seldomly reported. Most cases of metastatic osteosarcoma to the heart involve the myocardium rather than the pericardium. The right side of the heart is affected in 20–30% of cases and the left side in 10–33% of reported cases. Only 5% of cases affect the endocardium or chamber cavities. Clinical signs and symptoms of metastatic cardiac neoplasms include dyspnea, cough, chest pain, palpitations, superior vena cava syndrome, right ventricular outflow tract obstruction and pericardial effusion [1].

Keywords:Cardiac Osteosarcomas; GM-CSF autoantibodies; Autoimmune