Open Access Case Report

One Case of Refractory Condyloma Acuminatum in Children with Persistent HPV51 Infection Treated by Chinese Medicine Paiteling

Yang Meng1,2, Huang Yaohui1, Li Jianmin1, Lin Xiujuan1, Pan Yanbin1, and Zhu Qinghuan2,

1Department of Dermatology, the third affiliated hospital of Guangxi Medical University, 13 Dancun Road, Nanning 530031, Guangxi, Chinas

2Department of Dermatology, the second affiliated hospital of Kunming Medical University, Kunming, 650101, Yunnan, China

Corresponding Author

Received Date: February 26, 2020;  Published Date: April 07, 2020


A 3-year-old female presented with neoplasms on the perianal for1 month.

Physical examination: Multiple needle tips appearing around the anus to millet size. A few vegetations are seen at the vaginal opening. Human papilloma virus (HPV).

Typing: HPV51 positive. HIV, TPPA, and RPR tests were negative.

Histopathology of skin lesions: hyperkeratosis of the epidermis with incomplete keratosis, hyperplasia and hypertrophy of the spinous layer, papilloma-like hyperplasia, vacuolated cells seen above the spinal layer.

Diagnosis: Condyloma acuminatum.

Treatment: 4 times of photodynamic therapy was ineffective, HPV-51 continued to be positive, and then switched to the Chinese medicine Paiteling three-stage therapy. No new warts were found after follow-up for 1 year, and the HPV-51 turned negative.

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