Open Access Review Article

Molecular and Biochemical Outcomes of Exercise: A Review Study

Ahed J Alkhatib1,2*

1Department of Legal Medicine, Toxicology of Forensic Science and Toxicology, School of Medicine, Jordan University of Science and Technology, Jordan

2Department of Medicine and Critical Care, Department of Philosophy, Academician Secretary of Department of Sociology, International Mariinskaya Academy, Jordan

Corresponding Author

Received Date: October 09, 2019;  Published Date: October 18, 2019

Abstract

This study expressed the results of our works for about 10 years regarding exercise health effects. Physical exercise has been found to have significant effects under physiological conditions and pathologic conditions such as diabetes, Parkinson’s disease, osteoporosis, and others. Molecular effects of physical exercise were shown through up-regulation of some mediators in some pathways that include HSP70, VEGF, P16; and downregulation of some mediators in other pathways that include iNOS, P53, and estrogen receptor. These cellular variations act to make better health. Studies in osteoporosis revealed that physical exercise improves the health of bone through increasing levels of calcium and bone mineral density. Taken together, physical exercise improves the health of various body systems and organs and helps in protection and therapeutic conditions.

Keywords: Physical exercise; Up-regulation; Down-regulation; HSP70; VEGF; P16; P53; iNOS; Calcium

Citation
Signup for Newsletter
Scroll to Top