Invasive Mole with Nephrotic Syndrome: A Case Report with Literature Review

Nephrotic syndrome(NS)associated with invasive mole (IM) is uncommon. In this report, we present a case of NS that developed from IM. A 22-year-old woman was admitted to our hospital because of left lower slightly abdominal pain with sparing vaginal bleeding and NS. Transabdominal ultrasound examination confirmed a regular shape, border clearance component with a typical honeycomb pattern in the left side of the uterus. The curettage was performed for her two times. A renal biopsy was performed and suggested minimal change disease (MCD). Interestingly, when the IM was removed, her NS was complete remission. We report the rare case to highlight the importance of considering that NS associated with IM should be kept in mind during management of a woman of childbearing age with renal involvement.

Keywords: Invasive mole; Nephrotic syndrome; Gestational trophoblastic neoplasia; hydatidiform mole