Research Article
A Charge Transfer Determination of Paracetamol with Picric Acid
Department of Chemical Engineering, Madonna University (Akpugo Campus) Enugu State, Nigeria
Received Date:September 13, 2018; Published Date: October 03, 2018
Abstract
A cost effective and sensitive spectrophotometric method has been developed for the assay of paracetamol in pure and commercial forms. The method employed was charge transfer complexation. Paracetamol formed a 1:2 stoichiometric ratio with picric acid. The complex was quantified at 500nm. Beer –Lambert’s law was obeyed within a concentration range of 5-10ug/ml with molar absorptivity of 2.6 x104Lmol-1cm-1. The method was used for the determination paracetamol in pure and commercial forms with percentage mean recovery of 95%.
Keywords: Paracetamol; Picric acid; Charge transfer complex
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