Treatment of Infected Tibial Non-union: A Systematic Review and Meta-Analysis

Objectives: The aim of this work is to systematically review and make meta-analysis for treatment of the infected non-union of the tibia.

Methodology: A systematic review was completed, Study objective and comprehensive literature search were performed from the SCI, PubMed, Cochrane Library; and Embase between January 2000 and Feb. 2019. Some major data were statistically analyzed including number of patients, manage, external fixation time, Searches will be performed in the MEDLINE, Life Science Citations, PubMed, Google Scholar and EMBASE Biochemical (http://www.embase.com) databases will be accessed to search studies with no limits set during research, Terms aimed at capturing the target diagnosis, such as “infected tibial nonunion” and “fixation” were combined using the Boolean operator “or” and MeSH terms.

Result: 318 abstracts were identified during the search, 10 were excluded, 308 full articles were fully reviewed, 295 articles were excluded, 13 studied matched the inclusion criteria and were included in this review, 2 additional articles were identified during searching, a total 652 patients of 15 studies were presented in this systemic review.

Conclusion: Radical debridment of the infected non-union is mandatory, a satisfactory bone results and functional results were obtained. On the other hand Ilizaov technique proved as the most useful method in the treatment of the infected non-union of the tibia.

Keywords: Tibial; Nonunion; Infected; Ilizarov