Open Access Mini Review

Is there still some reason for classic presentation of Amyotrophic Lateral Sclerosis described in the literature?

Marco Orsini1*, Acary Souza Bulle Olveira2, Carlos Henrique Melo Reis3, Jacqueline Fernandes do Nascimento3, Nicolle Nunes3, Antônio Marcos da Silva Catharino3, Valéria Camargo Silveira3, Adriana Leico Oda2, Mauricio Santanna Júnior4 and Marcos RG de Freitas5

1University of Iguaçu and University of Vassouras, Brazil

2Federal University of São Paulo, Brazil

3Iguaçu University and Hospital Geral da Posse, Brazil

4Federal University of Rio de Janeiro, Brazil

Corresponding Author

Received Date: June 19, 2021;  Published Date: July 09, 2021

Obviously, a lot has changed regarding Amyotrophic Lateral Sclerosis (ALS). That old and exemplary definition made by Chacort, of a neurological disease, of a progressive, degenerative and inexorable character, with “isolated” depletion of the upper and lower motor neurons no longer seems so limited to words. ALS is already considered a systemic disease; not only because of new findings that circumvent motor manifestations, but because of genetic codes that signal a form of evolution of hereditary cases. Speaking of that 5-8 year survival after the onset of the first signs and symptoms, the increase in new technologies, associated with a different way of medicating and treating, changed the natural history of book chapters; even with the cruelty with which it strips and compromises patients in various topics related to their functional abilities. We are looking for a picture of Amyotrophic Lateral Sclerosis described in detail in the literature [1-2].

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