Effectiveness of Dexmedetomidine as a Coadyuvant in Analgesia and Epidural Anesthesia in Hysterectomies
Received Date: January 08, 2020; Published Date: January 21, 2020
Introduction:: Dexmedetomidine is an alpha-2 agonist that has sympatholytic, sedative, analgesic and sedative properties at the central level, which can be used as an adjuvant to anesthetics and analgesics at epidural and peripheral levels, prolonging and accelerating their action due to their properties Fat-soluble and high affinity for adrenoceptors and thus reduce their side effects. Add adjuvants to local anesthetics for better and more rapid testing at the beginning of the block, prolonging their duration, action and postoperative analgesia with lower doses of local anesthetics. Adjuvants such as opioids are used for this activity coupled with its side effects such as pruritus, urinary retention, nausea or vomiting.
Material and Methods: A prospective, comparative, randomized, blind, longitudinal study was conducted. 24 patients scheduled for elective hysterectomy were invited to participate in the study, of which 2 were eliminated due to a change in anesthetic technique.
Results: When assessing the time in which the patients reached a maximum sensory level, they found that patients in the dexmedetomidine group required a longer time (11.8 ± 4.6 vs. 6.3 ± 2.4 minutes, P = 0.002), however, we found no differences in the dorsal level of maximum sensory level (P = 0.23), in addition, the motor level time was greater in dexmedetomidine patients (17.2 ± 7.2 vs. 9 ± 2.6, P = 0.002).
Conclusion:Dexmedetomidine is a useful medication for analgesia and anesthesia in elective patients with hysterectomy compared to fentanyl, and the safety profile is similar in both anesthetics. In addition, we found that patients with dexmedetomidine take a longer time to reach their maximum sensory and motor level, so that they could gently prolong the surgeries.
Keywords:Dexmedetomidine; Adjuvant; Epidural anesthesia; Hysterectomy