Continuous Spike and Waves During Slow Sleep in the
Neurological Department of Fann National University
Hospital of Dakar: Topographic Aspects and Age

SECK Lala Bouna; SARR Mamadou Moustapha; AKRIM Hanane; KA Mamadou; DIOP Alassane Mamadou; GAYE Arame; DIOP-SENE Marème Soda; BASSE FAYE Anna Modji; BASSE FAYE Anna Modji; NDIAYE Moustapha; DIOP Amadou Gallo

Research Article

Continuous Spike and Waves During Slow Sleep in the Neurological Department of Fann National University Hospital of Dakar: Topographic Aspects and Age

SECK Lala Bouna¹, SARR Mamadou Moustapha², AKRIM Hanane³, KA Mamadou³, DIOP Alassane Mamadou3, DIOP-SENE Marème Soda⁴, GAYE Arame³, BASSE FAYE Anna Modji⁴, SOW Adjaratou Djeynabou⁴, NDIAYE Moustapha⁴ and DIOP Amadou Gallo⁴

^{1Department of Medical Specialties, Gaston Berger University of Saint Louis, Senegal}

^{2Department of Medical Specialties, Thies University, Senegal/p>}

^{3Department of Neurological, Fann National University Hospital, Senegal}

^{4Department of Medical Specialties, Cheikh Anta Diop University, Senegal}

Corresponding Author

Received Date: January 27, 2020; Published Date: February 05, 2020

Abstract

Introduction: Continuous spikes and waves during slow sleep (CSWS), are characterized by marked activation of epileptic activity on electroencephalographic (EEG) recording during slow sleep. Their topographic distribution is not homogeneous, and this could be not random. The aim of our study is to describe topographic aspects of CSWS and look for correlation with patients age.

Patients and methods: We conducted a descriptive retrospective study in the neurophysiological department of the neurological service of Fan national university hospital in Dakar (Senegal), over a 2 years period. We studied topographical aspects of EEG anomalies of children whose recordings presented CSWS, then looked for correlation between the predominant diffusion region of these and the age of patients.

Results: The CSWS were found on 1.02% of the global sample EEG and 2.60% of the children EEG. The sex-ratio was 1.42. The age varied from 3 to 14 years at the time of the first recording with a mean age of 6.65 +/- 2.63 years. The predominant age group was 3 to 8 years (81%). The main indications were generalized tonico-clonic seizures, focal seizures and benign epilepsy with centro-temporal spikes. CSWS were predominant on the left hemisphere on awake as well as sleep EEG. During waking state, the basal activity was normal on 96.97% of the recordings, anomalies were found on 96.97%, and the major diffusion location were the peri-sylvian regions. Sleep architecture was altered for 63.49% of patients. Topographically, CSWS diffused predominantly in the temporal, central and frontal regions. Children with anterior predominant diffusion of CSWS were older than those with posterior predominant diffusion and the difference was statistically significant (p = 0,031).

Conclusion: CSWS topographic distribution is variable and likely age-related. Given that brain areas have functionnal specificities, this could orient neuropsychological tests in cognitive deficits.

Keywords: Fann; Continuous; Spikes; Waves; Sleep; Topographic; Age

Abbreviations: CSWS: Continuous Spikes and Waves During Slow Sleep; EEG: Electroencephalographic, Electroencephalogram; Or: Odds Ratio; CI: Confidence Interval

Article Details

Citation

SECK Lala Bouna, SARR Mamadou Moustapha, AKRIM Hanane, KA Mamadou, DIOP Alassane Mamadou, et al. Continuous Spike and Waves During Slow Sleep in the Neurological Department of Fann National University Hospital of Dakar: Topographic Aspects and Age. Arch Neurol & Neurosci. 6(5): 2020. ANN.MS.ID.000650.