Open Access Research Article

Survival Rate Estimation of Advanced Carcinoma Prostate Patients by using Bone Scan Quantitative Parameters

Nayab Mustansar*

Women Medical College, Abbottabad, Pakistan

Corresponding Author

Received Date: July 11 , 2019;  Published Date: July 16, 2019

Abstract

There are several methods to-date which can be used to analyze the extent of such lesions. For example, quantitation of the bone scan using quantitation methods i.e. % BSI (Bone scan index), % PAB (Positive area on bone scans), EOD (extent of disease) and BLS (Bone lesion scoring). These methods are used for prognostication of survival and response to treatment on serial scans. 40 patients with histopathologically proved prostate cancer were chosen to implement all the four quantitative parameters on individual baseline bone scans and serial follow up scan were performed to calculate 2-years survival rate. After which, survival rate was calculated. The dataset was again analyzed using the four bone scan quantitative parameters and the cut off were calculated as % BSI: 1, % PAB: 0.5, EOD: grade 0 & 1, grade2, 3 & 4 and BLS: 5. It was found out that the %PAB and % BSI methods are good prognostic indicator in baseline scans. Moreover, the prostate cancer patients with the cut off % BSI >1, %PAB > 0.5, BLS >5 and EOD with grade 2, 3 & 4 showed increase risk of disease progression and less survival.

Keywords: Prostate cancer; Tumours; Cancer; PAB; BSI; Carcinoma

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