Open Access Mini Review

The Resurgence of Mucormycosis in the Covid-19 Era – A Review

Amit Bhardwaj1, Kratika Mishra2*, Shivani Bhardwaj3, Anuj Bhardwaj4

1Department of Orthodontics and Dentofacial Orthopaedics, Modern Dental College and Research Centre, Indore, India

2Department of Orthodontics and Dentofacial Orthopaedics, Index Institute of Dental Sciences, Indore, Madhya Pradesh, India

3Department of Prosthodontics, College of Dental Sciences, Rau, Madhya Pradesh, India

4Department of Conservative Dentistry and Endodontics, College of Dental Sciences, India

Corresponding Author

Received Date: June 7, 2021;  Published Date:June 25, 2021

Abstract

Mucormycosis (MCM) is a life-threatening infection that carries high mortality rates with devastating disease symptoms and diverse clinical manifestations. This article briefly explains clinical manifestations and risk factors and focuses on putative virulence traits associated with mucormycosis, mainly in the group of diabetic ketoacidotic patients, immunocompromised patients. The diagnosis requires the combination of various clinical data and the isolation in culture of the fungus from clinical samples. Treatment of mucormycosis requires a rapid diagnosis, correction of predisposing factors, surgical resection, debridement and appropriate antifungal therapy. The overall rate of mortality of mucormycosis is approximately 40%.

Keywords:Amphotericin B, emerging, Mucorales, mucormycosis, zygomycetes

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