The Mechanism of Single Progesterone as Add-Back
Therapy to GnRH-a Administration

Jiming Chen; Junling Liu; Weiwei Wei; Ying Cao; Yilin Sun; Huichao Xiao; Yafeng Zheng; Yunfen Jiang; Ruxia Shi

Opinion

The Mechanism of Single Progesterone as Add-Back Therapy to GnRH-a Administration

Jiming Chen, Junling Liu, Weiwei Wei, Ying Cao, Yilin Sun, Huichao Xiao, Yafeng Zheng, Yunfen Jiang and Ruxia Shi*

Department of Obstetrics and Gynecology, The Affiliated Changzhou NO. 2 People’s Hospital of Nanjing Medical University, Changzhou, 213000, China

Corresponding Author

Received Date: January 02, 2019; Published Date: January 04, 2019

Abstract

Endometriosis (EMS) is a common estrogen-dependent gynecological disorder, which affects quality of life and fertility of productive-aged women [1]. Current treatment of EMS is mainly based on surgery and post-operative maintenance treatment of ovarian suppressive agents. A major challenge for women with EMS is the post-operative recurrence [2-3]. Some medical treatments have been suggested for EMS, such as oral contraceptive pills, and gonadotropin-releasing hormone agonists (GnRH-a). GnRH-a is an important treatment modality for EMS, significantly reducing EMSrelated symptoms [4-6].

Article Details

Citation

Ruxia Shi, Jiming Chen, Junling Liu, Weiwei Wei, Ying Cao, et al. The Mechanism of Single Progesterone as Add-Back Therapy to GnRH-a Administration. W J Gynecol Women’s Health. 1(5): 2018. WJGWH.MS.ID.000521.