Open Access Opinion

Chronic Hypertension During the First Trimester of Pregnancy: What is New About the Use of Angiotensin- Converting Enzyme Inhibitors?

Lucas Soares Bezerra1*, Marcelo Antônio Oliveira Santos-Veloso1 and Sandro Gonçalves de Lima1,2

1Maurício de Nassau University, Brazil

2Federal University of Pernambuco, Brazil

Corresponding Author

Received Date: February 15, 2019;  Published Date: February 20, 2019

Abstract

Cardiovascular diseases are a major cause of maternal mortality and morbidity worldwide, including developed countries [1]. The first-line drug to treat hypertension in pregnant women is methyldopa, which is an α2-adrenergic agent that has shown maternal and fetal safety and efficacy. However, methyldopa is not effective in all cases, and sometimes it is important to consider other pharmacological agents [1,2].

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