Open Access Review Article

An Overview of the Basic Knowledge of Levonorgestrel-Releasing Intrauterine System

Junling Liu, Mengyue Chen, Zhiyong Dong, Shoufeng Zhang, Wendi Zhang, Zhenyue Qin and Chen Jiming*

Department of Obstetrics and Gynecology, The Affiliated Changzhou NO. 2 People’s Hospital of Nanjing Medical University, Changzhou, 213000, China

Corresponding Author

Received Date:May 24, 2021;  Published Date: June 07, 2021


Levonorgestrel-releasing Intrauterine system (LNG-IUS, Mirena) is a very safe, efficient, long-acting and reversible intrauterine device, which releases high-efficiency at a daily dose of 20ug Progesterone mainly acts on the part of the endometrium, causing the endometrial glands to shrink. A large number of studies have fully proved that LNG-IUS is not only effective in contraception, but also widely used in non-contraceptive fields. LNG-IUS is effective in treating gynecological diseases such as menorrhagia and dysmenorrhea. In addition, LNG-IUS is also used in endometriosis, adenomyosis, endometrial polyps, endometrial hyperplasia, and early endometrial cancer. Reversal of cancer and endometrial protection in breast cancer patients. This article will briefly summarize the basic knowledge of LNG-IUS and the clinical application of LNG-IUS in gynecological diseases.

Keywords: Levonorgestrel-releasing Intrauterine system; Mirena; High-efficiency progesterone; Long-acting reversible contraception

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