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Scientific Journal of Research & Reviews - SJRR

ISSN: 2687-8097

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Open Access Mini-Review

Hyperbranched Poly (Ester)S from renewable Bio Monomers by Design: Nontoxic Platforms for the delivery of therapeutic agents

Bob A Howell1*, Tracy Zhang1,2 and Patrick R Smith1

1Department of Chemistry and Biochemistry, Central Michigan University, USA

2Michigan State University-St. Andrews, USA

Corresponding Author

Received Date: September 19, 2019;  Published Date: October 11, 2019

Synopsis

Hyperbranched poly(ester)s from adipic or succinic acid and glycerol generated under conditions which permit high monomer conversion without gelation and assure the presence of hydroxyl endgroups may serve as effective platforms for the delivery of therapeutic agents. Active agents may be attached by esterification at the end groups. Smooth, sustained release of the therapeutic agent may be achieved hydrolytically.

Article Details
Citation

  • Bob A Howell, Tracy Zhang, Patrick R Smith. Hyperbranched Poly (Ester)S from renewable Bio Monomers by Design: Nontoxic Platforms for the delivery of therapeutic agents. Sci J Research & Rev. 2(2): 2019. SJRR.MS.ID.000531.

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