Open Access Research Article

Systolic, Diastolic Blood Pressure, LDL-C and HDL-C Correction by Fruits and Allopathic Medications

Abdul Azim Azmi1, Altaf Hussain2, Dureshwar Marwat3, Shah Murad4 * and Adnan Shafique5

1Department of pharmacology, Islam Med College, Pakistan

2Research fellow at ICCBS, HEJ, Pakistan

3Department of Forensic Medicine, IMDC/ANTH, Pakistan

4Department of Pharmacology, IMDC, Pakistan

5Department of Clinical Pharmacist at MCC Pharmacy, Pakistan

Corresponding Author

Received Date: December 16, 2019;  Published Date: January 13, 2020


There are ethnic-based medicinal herbs which can be used to treat or prevent CAD with narrow to moderate range of statistical significance. We compared Rosuvastatin 10 mg with Indian dates (Jujubes) as hypolipidemic agents. This research was conducted at Ghurki Trust Teaching Hospital, jalo park, Lahore, Pakistan. Duration of study was two months. Twenty to seventy years old 60 hyperlipidemic patients of both genders were included in research work with written consent. We divided these patients in two equal groups. Group-I was advised to take Tablet Rosuvastatin 10 mg, twice daily for two months. Group-II was advised to take 500 grams Indian dates for two months. Their baseline parameters like LDL-cholesterol, HDL-cholesterol, systolic/diastolic blood pressure was determined in the hospital laboratory. Separate file was maintained for their name, age, sex, occupation, and address. After two months therapy we compiled data related to tested parameters. Paired t-test was applied to compare changes in all parameters. Their mean values with ± SD before and after treatment were compared and analyzed statistically. It was observed that Rosuvastatin significantly decreased systolic/diastolic blood pressure, LDL-cholesterol, and increased HDL-cholesterol in 27 hyperlipidemic/hypertensive patients. Indian dates used in 30 hyperlipidemic patients significantly decreased systolic blood pressure, and LDL-cholesterol, but insignificant changes were seen in diastolic blood pressure, and HDL-cholesterol. We concluded from the research work that Rosuvastatin is potent hypolipidemic and hypotensive medicine as compared to Indian dates.

Keywords: Shah Murad, Department of Pharmacology, Hod therapeutics at Akbar Niazi Hospital and Islamabad Medical & Dental College, Islamabad, Pakistan.

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