Mini Review
Thrombolysis: The Current State of The Art and How it can be Improved
Received Date: April 26, 2019; Published Date: May 03, 2019
Abstract
Current thrombolytic therapy is essentially synonymous with high dose tPA administered iv for 90 minutes. This treatment has had only limited success in acute myocardial infarction (AMI) [1-3], and consequently has more recently been replaced by percutaneous coronary intervention (PCI) as the treatment of choice in AMI [4]. Although PCI delays coronary reperfusion, better clinical outcomes than with tPA were nevertheless obtained [5]. In the treatment of ischemic stroke, a tPA dose reduction was required due to a 20% intracranial hemorrhage (ICH) incidence when the AMI dose was used [6].
Signup for Newsletter
