Brazilian Lipid Cardiovascular Risk Pre and During the Covid 19 Pandemic in Asymptomatic and Severely Affected Groups

The COVID 19 pandemic still keeps investigators, public health representatives and patients in a state of extreme worry all around the world. Investigations of the hazardous influences played by the comorbidities have to be carried on with more details than ever opening new avenues for it’s’ understanding. In this paper there was a clear statistical response for worse in the lipids and lipoprotein profiles starting from the prepandemic to the pandemic, both asymptomatic groups, maintaining the worsening in the very severely affected that had to be admitted to the Intensive Care Units, analyzing the use of hypolipidemic medications as well. The modern use of encrypted emails sending with confidentiality all the results to one specific software center enables the investigators to carry on a research with a certain similarity to a national survey. The means of all lipid analytes were significantly different between the pre and post-pandemic cohorts (2018+2019 and 2020). It also shows that the frequency of participants with altered results for total cholesterol, triglycerides, and HDL-c and with dyslipidemia were also significantly different between the two cohorts. The year of 2020 had a higher mean of lipid analytes than the pre-pandemic years of 2018 and 2019 combined. The frequencies of participants with total cholesterol above 190 mg/dL and triglycerides above 175 mg/dL were both higher in 2020 than 2018 and 2019, and the frequency of those with dyslipidemia was also significantly greater for that cohort. Besides all the medical information for each of the patients this database in full can be used for public health policies.

Keywords:19; Total Cholesterol; LDL Cholesterol; HDL Cholesterol; VLDL Cholesterol; Non HDL Cholesterol; Pandemic changes; Pre pandemic

Abbreviations:HDL: High Density Lipoprotein; HDL-c: HDL Cholesterol; LDL: Low Density Lipoprotein; POCT: Point-of-Care testing; TG: Triglycerides; VLDL: Very Low Density Lipoprotein