In Vitro Assessment of Dermal Absorption for Flame Retardant Textile Finishing Chemicals

Flame Retardants are a group of anthropogenic environmental contaminants used in textile finishing’s. Currently, the largest marked group of FRs is brominated FR considered toxic, persistent and bio accumulative. Non-halogenated alternatives are a possible solution, but there is a lack of knowledge concerning environmental impact and health risks.

The aim of this study is focused on dermal absorption of FR in order to calculate the Margin of security for textile fabrics treated with flame retardant finishing’s. FR based on sulfamate ammonium were used applied onto cotton and polyester fabrics. Both have been demonstrated that they are dermal safety for human at the conditions used.

Keywords: Flame retardants; Percutaneous absorption; MoS; Sulfamate ammonium; Cotton; Polyester

Abbreviations: FR: Flame Retardant; OECD: Organization for Economic Cooperation and Development: MoS: Margin of Security; SED: Systemic Exposure Dose; NOAEL: Non-Observed Adverse Effect Level