Down’s syndrome and Alzheimer Disease Imaging

Genetics

Ahmed Bashir MD, PhD; Stanley Nelson MD

Mini Review

Down’s syndrome and Alzheimer Disease Imaging Genetics

Ahmed Bashir MD, PhD¹* and Stanley Nelson MD²

Department of Pediatrics, Al Mana General Hospital, Jubail, P.O. BOX10366, 113 Al Hawailat Street, K.S.A, 31961

Professor of Genetics, David Geffen Medical School, UCLA,CA, USA

Corresponding Author

Received Date: December 17, 2018; Published Date: January 24, 2019

Abstract

The advancement of both in vivo imaging modalities that detect the neuropathologist associated with both Down’s syndrome and Alzheimer’s disease present new opportunities to explore these diseases in living human subjects. Previously, these neuropathologists could not be detected until after autopsy or in the living patient, with the rarely taken brain biopsy. The use of quantitative traits derived from these imaging modalities offers increased power to detect associations with large scale genetic data, and these studies fall under the category of imaging genetics.

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