Influence of Different Counting Parameters for
the Measurement of Thyroid and Thyroid Related
Hormones Using Radio Immuno Assay (RIA)
Technique and 125I Isotopes

Md Anwarul Kabir Bhuiya; Raihana Ferdaws; Abu Mahmud; Md Abdul Halim; Md Shahnewaz Parvez; Shefali Khatun; Nasrin Laz; Md Shariful Islam Chowdhury

Research Article

Influence of Different Counting Parameters for the Measurement of Thyroid and Thyroid Related Hormones Using Radio Immuno Assay (RIA) Technique and 125I Isotopes

Md Anwarul Kabir Bhuiya¹*, Raihana Ferdaws¹, Abu Mahmud¹, Md Abdul Halim¹, Md Shahnewaz Parvez¹, Shefali Khatun², Nasrin Laz² and Md Shariful Islam Chowdhury²

¹Department of Materials Science and Engineering, University of Rajshahi, Rajshahi, Bangladesh

²Institute of Nuclear Medicine and Allied Sciences (INMAS), BAEC, Rajshahi, Bangladesh

Corresponding Author

Received Date: March 10, 2019; Published Date: May 07, 2019

Abstract

Different methods for the determination of thyroid and related hormone have been reviewed. Performance characteristics of the radio isotopic method for the hormone assay were identified. Bound T3, Bound T4, TSH and Free T4 were assayed using different counting time and two different pulse height window levels. A very little difference was found during the measurement. The whole procedure was performed using Canberra AccuSpec NaI system, which has a high precision and stability. (c Squire equals to 3.56, detector resolution 9.10% and a 2k channel MCA). It is noticed that for low counting measurement counting time and window effect are present. It is assumed that for analog devices with single channel system the difference may be significant.

Keywords:Radio Immuno Assay (RIA), Counting time; Window levels; Radioactive Materials; Gamma Camera; Thyroid Hormones

Article Details

Citation

Md Anwarul Kabir Bhuiya, Raihana Ferdaws, Abu Mahmud, Md Abdul Halim, Md Shahnewaz Parvez, et al. Influence of Different Counting Parameters for the Measurement of Thyroid and Thyroid Related Hormones Using Radio Immuno Assay (RIA) Technique and 125I Radioactive Isotopes. Glob J Eng Sci. 2(2): 2019. GJES.MS.ID.000531.