Atypical clinical presentation of COVID-19: a case of Guillain-Barrè Syndrome related to SARS-Cov-2 infection

In these months the diffusion of a novel beta coronavirus, known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is causing a worldwide public health emergency originated in Wuhan, China. SARS-CoV-2 infection may develop asymptomatic or begin with mild flu-like symptoms, but in severe case it causes the so called “Coronavirus Disease 2019” (COVID-19), characterized by serious interstitial pneumonia that may quickly develop into severe acute respiratory distress syndrome (ARDS), septic shock, sepsis-induced coagulopathy and fatal multi organ dysfunction.

Emerging evidence indicates that SARS-CoV-2 infection can also cause neurological manifestations. In this report we describe an atypical clinical presentation of COVID-19, started as Guillain-Barré syndrome (GBS) and without typical respiratory symptoms of SARS-Cov-2 disease.

Keywords: COVID-19; Guillain-Barrè Syndrome; SARS-CoV-2 infection