Open Access Opinion

Inheritance of Susceptibility to Malignant Blood Disorders

Viggo Jonsson*1,2, Haneef Awan2,3, Neil D Jones4, Tom B Johannesen5, Bjarni a Steig6,7, Gudrid Andosdottir7 and Geir E Tjonnfjord 1,2

1Department of Hematology, Oslo, Norway

2Institute of Clinical Medicine, Oslo, Norway

3Department of Research Computing, Oslo, Norway

4Department of Computer Science, Copenhagen, Denmark

5Norwegian Cancer Registry, Oslo, Norway

6Department of Medicine, Torshavn, the Faroe Islands

7Genetic Biobank, Torshavn, the Faroe Islands

Corresponding Author

Received Date: March 18, 2019;  Published Date: March 27, 2019


This is a study of familial malignant blood disease (MBD), both lymphoproliferative (LPD) and myeloproliferative (MPD). One group is from Norway and Denmark: 112 families with unrelated parents, in all 301 cases of MBD. This group is compared with 315 patients with MBD from the Faroe Islands. The Faroese population is in effect one large inbred family with related parents. LPD includes the lymphoid leukemias (chronic and acute), the malignant lymphomas (morbus Hodgkin and non-Hodgkin’s lymphomas), multiple myeloma and a few other diagnoses. MPD includes the myeloid leukemias (chronic and acute), myelodysplasia, myelofibrosis, polycythemia vera and essential thrombocytosis.

Signup for Newsletter
Scroll to Top