Short Communication
Decreased Joint Pain Associated with Curcumin Use
in a Controlled Study for Alzheimer’s Disease: A
Serendipitous Observation
John M Ringman1, Greg M Cole1,2 and Sally Frautschy*1,2
1Department of Neurology, Mary S Easton Center for Alzheimer’s Disease Research, USA
2Department of Neurology, Geriatric Research Education and Clinical Center, USA
John M Ringman1, Greg M Cole1,2 and Sally Frautschy*1,2
1Department of Neurology, Mary S Easton Center for Alzheimer’s Disease Research, USA
2Department of Neurology, Geriatric Research Education and Clinical Center, USA
Sally Frautschy, Geriatric Research Education and Clinical Center, WLA Veterans Administration Medical Center, USA.
Received Date: January 06, 2020; Published Date: January 21, 2020
Abstract
Curcumin is a natural product with anti-inflammatory properties for which there is preliminary evidence of efficacy in the treatment of arthritis. We performed a 24-week, randomized, placebo-controlled, and blinded study of curcumin for Alzheimer’s disease in which there was a 24-week open-label extension. At each visit, subjects and their informants were specifically queried about adverse events with a comprehensive checklist that included the presence or absence of joint pain. We serendipitously found a dose-dependent trend for decreased reports of joint pain. This observation provides evidence for the efficacy of curcumin for the treatment of joint pain in the elderly.
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Sally Frautschy, John M Ringman, Greg M Cole. Decreased Joint Pain Associated with Curcumin Use in a Controlled Study for Alzheimer’s Disease: A Serendipitous Observation. Arch Rheum & Arthritis Res. 1(1): 2020. ARAR.MS.ID.000503.
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