Behind the Scenes Of Cns Vasculitis: A Rare Case of Cns
Vasculitis with Two Primary Malignancies

Lindsay Smith

Case Report

Behind the Scenes Of Cns Vasculitis: A Rare Case of Cns Vasculitis with Two Primary Malignancies

Savvina Prapiadou¹, Daniel Woo², Adam Koss², Andrew Creed², Rina Mina³, Priyanka Vashisht³, Kristina Brannock⁴, Mosaab Mohameden³*

¹Department of Medicine, University of Patras College of Medicine, Greece

²Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, USA

³Department of Internal Medicine, Rheumatology Division, University of Cincinnati College of Medicine, USA

⁴Department of Pathology, University of Cincinnati College of Medicine, USA

Corresponding Author

Received Date: July 09, 2021; Published Date: October 05, 2021

Abstract

To highlight the importance of a broad differential diagnosis, including malignancy, in patients with central nervous system vasculitis (CNSV) presenting as multiple, recurrent cryptogenic strokes.

Recent Findings

We describe a rare entity, CNSV in the setting of two underlying neoplastic disorders and a chorioretinal inflammatory disease. The clinical presentation, imaging study results, histopathologic features, and response to treatment are reported.

Summary

Cancer-associated CNSV is a rare cause of recurrent cryptogenic strokes. This case highlights the importance of clinical suspicion of and comprehensive work-up for neoplasms in a patient presenting with brain lesions consistent with CNSV.

Keywords: Vasculitis; Infarction; Visual loss; Retina; Paraneoplastic syndrome

Abbreviations:

APMPPE- Acute posterior multifocal placoid pigment epitheliopathy

CNSV- Central Nervous system Vasculitis

MRI- magnetic resonance imaging

MRA- magnetic resonance angiography

ANA- anti-nuclear antibody

CSF- Cerebrospinal fluid

PET- positron emission tomography

CT - computerized tomography

CYC- cyclophosphamide

Article Details

Citation

Andrew Creed, Rina Mina, Priyanka Vashisht, Kristina Brannock, Mosaab Mohameden etc all,... Behind the Scenes Of Cns Vasculitis: A Rare Case of Cns Vasculitis with Two Primary Malignancies. Arch Rheum & Arthritis Res. 1(5): 2021. ARAR.MS.ID.000521.