Open Access Opinion

Water Immersion-Induced Skin Wrinkling: More Accurately Reflects Neurovascular Coupling rather than Just Neural Function

Louis Salciccioli, Kamal Akbar, Fnu Urwa Tul Vusqa, Narges Khalili, Andrew Tom and Jason Lazar*

Department of Medicine, State University of New York, USA

Corresponding Author

Received Date: December 11, 2019;  Published Date: December 17, 2019


Skin wrinkling (SW) is a normal response to water immersion (WI) that is impaired after peripheral nerve injury. The mechanism appears to involve passive diffusion of water across the stratum corneum into the sweat ducts. This alters electrolyte balance and increases sympathetic neural firing causing vasoconstriction. SW results from a decreased digital volume relative to surface area. WISW has been suggested to be a measure of peripheral sympathetic function, to reflect autonomic function and small fibre neural function. Since this response involves both neural and vascular responses, we propose WISW to more accurately reflect neurovascular coupling.

Keywords: Water induced skin wrinkling; Sympathetic function; Vasoconstriction; Neurovascular coupling

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