Open Access Mini Review

The Role of Monoamine System in Core Affects and Basic Emotions

Fushun Wang1,2,3* and Yiyuan Tang4

1Department of Neurosurgery, University of Rochester Medical Center, USA

2Institute of Emotion, School of Psychology, Nanjing University of Chinese Medicine, China

1Department of Surgery, Baylor Scott & White Health, USA

1Department of Psychological Sciences, Texas Tech University, USA

Corresponding Author

Received Date: March 21, 2019;  Published Date: April 01, 2019


Affective disorders are a leading cause of disability worldwide, and drugs targeting monoamine neuromodulators are considered to be the first choice of treatment for these diseases. Here, we further explore the relationship between the monoamine neuromodulators with the core affects or basic emotions and try to give a very simple model for basic emotions: three primary color model. In this model, we try to put the 3 monoamines together with the core affects or basic emotions in a plane, like the threeprimary color: DA-reward (joy), NE- stress (fear and anger), and serotonin- punishment (sad). This model can be helpful to better understand the dynamics of basic emotions, the etiology of affective disorders such as depression, and the actions of respective psychoactive drugs.

Abbreviations: Basic emotions; Monoamine; Core affect; Dopamine; Norepinephrine; Serotonin; Stress; Reward; Punishment

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