Neuronal Malady in Epileptic Brain – Amendment with Mushroom

Epilepsy is a neurological disorder of the central nervous system usuallay manifested through frequent seizures. Though epileptic symptoms had been recognized since ancient times, it could not be kept under control. Its treatment strategy varies from culture to culture and society to society. Modern medicinal approaches to withstand epileptic signs and symptoms are yet to become fully successful. Thus, alternative, easy to reach, cheap and traditional and complementary medicine-based anti-epileptic therapeutic approaches have reached momentum. Here, we report the distorted neuronal status in epileptic brain, its causes and remedy through culinary and medicinal mushrooms, the macrofungi. Both edible and medicinal mushrooms seem promising in keeping the neuronal normalcy and also in recovering the distorted neuronal health of the epileptic subjects as manifested through anti-oxidative and neuroprotective attributes as manifested by the amelioration of frequency and duration of the seizures of the mushroom fed epileptic subjects.

Keywords:Anti-oxidant; Epilepsy; mushroom; Neuron; Oxidative stress; Reactive oxygen species