Research Article
Fenugreek Decreases Total Cholesterol, TGs, and LDL Cholesterol
Khalid Niaz1, Saleemullah Abro2, Sibghatullah Sangi3, Shah Murad4, Nusratullah Khan5, Moosa Khan6, Major Tarique Ahmed Maka7 and SM Baloch8*
1AP Pharmacology at Akbar Niazi Teaching Hospital, Islamabad-Pakistan
2Assistant Professor of Physiology, Baqai Medical University, Karachi Pakistan
3Pharmacology Department, Northern Border University, Arar, Saudi Arabia
4Professor at Akbar Niazi Teaching Hospital- IMDC, Islamabad-Pakistan
5Assistant Prof of Biochemistry at Bolan University of Medical and health Sciences, Quetta, Pakistan
6Chairman Pharmacology at SZABMU Islamabad Pakistan
7Otolaryngologist at CMH Mangla Pakistan
8Pharmacology Department, Akbar Niazi Teaching Hospital and IM&DC, affiliated with SZABMU, Islamabad, Pakistan
SM Baloch, Pharmacology Department, Akbar Niazi Teaching Hospital and IM&DC, affiliated with SZABMU, Islamabad, Pakistan.
Received Date: March 14, 2023; Published Date: March 21, 2023
Abstract
Study was conducted at Jinnah Hospital Lahore-Pakistan from January 2019 to May 2019. Ninety hyperlipidemic patients of age group 19 to 70 were included in the study. Exclusion criteria were diabetic, alcoholic additives, hypertensive patients and those whose kidney or liver functions were impaired. Consent was taken from all participants. Their base line lipid profile was taken in biochemistry laboratory of the hospital. They were divided in three groups i.e. 30 patients in each group. Group-I was advised to take 500 mg of Curcuma longa (haldi) mixed in fresh milk without cream, thrice daily for two months. Group-II patients were advised to take 100 grams of Fenugreek leaves mixed with salad in each meal (thrice daily) for the period of two months. Group-III patients were advised to take 40 ml of fresh lemon juice mixed with 40 ml mineral water thrice daily for two months. They all were advised not to take heavy meal rich with any type of fat like junk food etc. One hour daily brisk walk was advised to all participants. 15 days follow up visit was scheduled for them. After two months their lipid profile was re-determined. When results were compiled and statistically analyzed by applying paired ‘t’ test, it revealed that Curcuma longa decreased total cholesterol, TG, LDL cholesterol 16.10, 20.01, and 17.59 mg/dl respectively. Fenugreek decreased total cholesterol, TGs, and LDL cholesterol 14.70, 17.33, and 17.06 mg/dl respectively. Lemon in two months therapy decreased total cholesterol, TGs, and LDL cholesterol 15.45, 10.13, and 11.97 mg/dl respectively. None of the above mentioned herbs raised HDL cholesterol significantly. It was concluded from this research work that Curcuma longa, Fenugreek leaves and Lemon are mild to moderately effective hypolipidemic herbs to lower total plasma cholesterol, triglycerides, and LDL cholesterol but have no potential to raise HDL cholesterol when analyzed biostatistically.
-
Khalid Niaz, Saleemullah Abro, Sibghatullah Sangi, Shah Murad, Nusratullah Khan, Moosa Khan, Major Tarique Ahmed Maka and SM Baloch*. Fenugreek Decreases Total Cholesterol, TGs, and LDL Cholesterol. Arch Neurol & Neurosci. 14(4): 2023. ANN.MS.ID.000845.
-
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.