1p and 19q Chromosomes Loss of Heterozygosity and
Genetic Deletions Role in the Chemosensitivity of
Oligodendrogliomas

Behzad Saberi

Opinion

1p and 19q Chromosomes Loss of Heterozygosity and Genetic Deletions Role in the Chemosensitivity of Oligodendrogliomas

Behzad Saberi*

Medical Research, Iran

Corresponding Author

Received Date: July 15, 2019; Published Date: July 29, 2019

Abstract

Oligodendroglioma as a glial tumor originating from oligodendrocytes, is identified by positive stain for myelin basic protein and characterized by ‘fried-egg’ appearance histologically. It would be a low-grade tumor with slow growing pattern, but anaplasia and aggressive behavior also can be occurred. Due to the hemorrhage in the tumor, sometimes the tumor will be symptomatic abruptly. CT and MRI scans can be used to determine the tumor as it presents as a hypointense T1-lesion on MRI scans and a nonenhanced hypodense lesion on CT scans.

Article Details

Citation

Behzad Saberi. 1p and 19q Chromosomes Loss of Heterozygosity and Genetic Deletions Role in the Chemosensitivity of Oligodendrogliomas. Adv Can Res & Clinical Imag. 2(1): 2019. ACRCI.MS.ID.000530.