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Archives in Biomedical Engineering & Biotechnology - ABEB

ISSN: 2687-8100

Managing Editor: Lisa Resnick

NLM ID: 101749213

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Open Access Short Communication

Combining Biocatalysts and Semi-Synthesis to (Bio) Synthesize Recalcitrant Pharmaceuticals

Nik Kovinich*

Department of Plant and Soil Sciences, USA

Corresponding Author

Received Date: May 10, 2019;  Published Date: May 17, 2019

Abstract

Difficult-to-synthesize (recalcitrant) bioactive molecules can be (bio)synthesized using semi-synthesis and biocatalysis methods in tandem. Biocatalysts modules consist of promiscuous enzymes heterologously expressed in microbes that can accept semi-synthetic versions of natural products. The ordering of semi-synthesis and biocatalysis reactions can be changed to optimize the overall efficiency of (bio)synthesis.

Article Details
Citation

  • Nik Kovinich. Combining Biocatalysts and Semi-Synthesis to (Bio)Synthesize Recalcitrant Pharmaceuticals. Arch Biomed Eng & Biotechnol. 1(4): 2019. ABEB.MS.ID.000519.

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